A 7-year-old SF Miniature Poodle was presented for evaluation of several weeks duration of poor appetite, intermittent vomiting, and weight loss. On physical examination, mild dehydration and mild pain on palpation of the cranial abdomen was present. Abnormalities on CBC and serum biochemistry were hemoconcentration, leukocytosis, monocytosis, and neutrophilia, azotemia, hyperphosphatemia, and severely elevated ALT, ALP, and GGT activity.
Liver – acute hepatitis (viral, bacterial, toxins), neoplasia, abscessation, trauma
Gall bladder – cholecystitis, mucocele, neoplasia, obstruction (lith, duodenal/pancreatitic disease)
Pancreas – pancreatitis, neoplasia
None
Chronic cholecystitis. Mucocele formation with reactive fat.
There was no overt evidence of neoplasia.
The liver revealed mildly increased portal markings. The gallbladder presented thickened ill-defined wall with suspended debris and striating bile. This is consistent with chronic cholecystitis and mucocele formation.
Reactive fat was noted primarily associated with the neck of the gallbladder and continued to the right limb of the pancreas. However, the gallbladder is a primary issue in this case.
