A 10-month-old intact male toy poodle dog was presented for evaluation of acute onset of vomiting. Initial lab work had shown azotemia (creatinine 3.3, BUN 95), which progressively increased over 3 days (creatinine 9, BUN 151). Severe proteinuria was present on urinalysis.
A 10-month-old intact male toy poodle dog was presented for evaluation of acute onset of vomiting. Initial lab work had shown azotemia (creatinine 3.3, BUN 95), which progressively increased over 3 days (creatinine 9, BUN 151). Severe proteinuria was present on urinalysis.
Nephrosis with intratubular oxylates suggestive of antifreeze toxicity in a 10 month old MI miniature poodle
History
Clinical Differential Diagnosis
Acute renal failure – toxins (ethylene glycol), sepsis, trauma. Congenital renal disease with acute decompensation. Addison’s disease.
DX
Nephrosis with intratubular oxylates, ethylene glycol toxicosis
Sampling
Histopathology revealed moderate, acute, diffuse nephrosis with intratubular oxalates.
Sonographic Differential Diagnosis
Ethylene glycol toxicosis, other renal toxin, infectious disease (leptospirosis).
Image Interpretation
Both kidneys showed diffuse hyperechoic cortical changes and excessive cortex/medulla ratio.
Outcome
The patient was euthanized three days after presentation.
Video
Patient Information
Patient Name : Jaffe B
Age : 10 Months
Gender : Male, Intact
Species : Canine
Liz Wuz Here : Yes
Status : Complete
Code : 06_00081
Blood Chemistry
- Azotemia
Clinical Signs
- Vomiting
Urinalysi
- Protein Present
Images
